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Cardiovascular epigenetics

Section information

Section Editor : TBD

The impact of epigenetics in cardiovascular disease is now emerging as an important player at different levels from etiology to therapeutics. This section publishes original epigenetic research and reviews in all cardiovascular medical specialties from both animal model and human studies. Research that links epigenetic regulation with cardiovascular risk factors, biomarkers and subclinical cardiovascular diseases will also be included in this section.

  1. Content type: Research

    Recently, epigenetic age acceleration—or older epigenetic age in comparison to chronological age—has been robustly associated with mortality and various morbidities. However, accelerated epigenetic aging has n...

    Authors: Marguerite R. Irvin, Stella Aslibekyan, Anh Do, Degui Zhi, Bertha Hidalgo, Steven A. Claas, Vinodh Srinivasasainagendra, Steve Horvath, Hemant K. Tiwari, Devin M. Absher and Donna K. Arnett

    Citation: Clinical Epigenetics 2018 10:56

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  2. Content type: Research

    The high prevalence of obesity among US adults has resulted in significant increases in associated metabolic disorders such as diabetes, dyslipidemia, and high blood pressure. Together, these disorders constit...

    Authors: Tomi Akinyemiju, Anh N. Do, Amit Patki, Stella Aslibekyan, Degui Zhi, Bertha Hidalgo, Hemant K. Tiwari, Devin Absher, Xin Geng, Donna K. Arnett and Marguerite R. Irvin

    Citation: Clinical Epigenetics 2018 10:49

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  3. Content type: Research

    Early pulmonary oxygen exposure is one of the most important factors implicated in the development of bronchopulmonary dysplasia (BPD).

    Authors: Cho-Ming Chao, Rhea van den Bruck, Samantha Lork, Janica Merkle, Laura Krampen, Patrick P Weil, Malik Aydin, Saverio Bellusci, Andreas C. Jenke and Jan Postberg

    Citation: Clinical Epigenetics 2018 10:37

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  4. Content type: Research

    Alterations in DNA methylation are demonstrated in atherosclerosis pathogenesis. However, changing rules of global DNA methylation and hydroxymethylation in peripheral blood leukocytes (PBLs) and different blo...

    Authors: Qianyun Deng, Wei Huang, Chunyan Peng, Jiajia Gao, Zuhua Li, Xueping Qiu, Na Yang, Bifeng Yuan and Fang Zheng

    Citation: Clinical Epigenetics 2018 10:9

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  5. Content type: Review

    Aortic valve stenosis is the most common cardiac valve disease, and with current trends in the population demographics, its prevalence is likely to rise, thus posing a major health and economic burden facing t...

    Authors: Igor Gošev, Martina Zeljko, Željko Đurić, Ivana Nikolić, Milorad Gošev, Sanja Ivčević, Dino Bešić, Zoran Legčević and Frane Paić

    Citation: Clinical Epigenetics 2017 9:106

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  6. Content type: Research

    Excess adiposity in childhood is associated with numerous adverse health outcomes. As this condition is difficult to treat once present, identification of risk early in life can help inform and implement strat...

    Authors: Jacob K. Kresovich, Yinan Zheng, Andres Cardenas, Brian T. Joyce, Sheryl L. Rifas-Shiman, Emily Oken, Matthew W. Gillman, Marie-France Hivert, Andrea A. Baccarelli and Lifang Hou

    Citation: Clinical Epigenetics 2017 9:86

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  7. Content type: Short report

    Development of cardiovascular disease (CVD), including coronary artery disease, arrhythmia, and ischemic stroke, depends on environmental and genetic factors. To investigate the epigenetic basis of myocardial ...

    Authors: Masahiro Nakatochi, Sahoko Ichihara, Ken Yamamoto, Keiko Naruse, Shigeki Yokota, Hiroyuki Asano, Tatsuaki Matsubara and Mitsuhiro Yokota

    Citation: Clinical Epigenetics 2017 9:54

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  8. Content type: Research

    DNA methylation is a key epigenetic mechanism that is suggested to be associated with blood lipid levels. We aimed to identify CpG sites at which DNA methylation levels are associated with blood levels of trig...

    Authors: Kim V. E. Braun, Klodian Dhana, Paul S. de Vries, Trudy Voortman, Joyce B. J. van Meurs, Andre G. Uitterlinden, Albert Hofman, Frank B. Hu, Oscar H. Franco and Abbas Dehghan

    Citation: Clinical Epigenetics 2017 9:15

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  9. Content type: Short report

    Antisense non-coding RNA in the INK4 locus (ANRIL) fixed genetic variants have consistently been linked with coronary heart disease (CHD) risk. We investigated relationships between perinatal ANRIL promoter DN...

    Authors: Robert Murray, Jennifer Bryant, Phil Titcombe, Sheila J. Barton, Hazel Inskip, Nicholas C. Harvey, Cyrus Cooper, Karen Lillycrop, Mark Hanson and Keith M. Godfrey

    Citation: Clinical Epigenetics 2016 8:90

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  10. Content type: Research

    Gender, genetic makeup, and prior experience interact to determine physiological responses to an external perceived stressor. Here, we investigated the contribution of both genetic variants and promoter methyl...

    Authors: Ting Li-Tempel, Mauro F. Larra, Estelle Sandt, Sophie B. Mériaux, Andrea B. Schote, Hartmut Schächinger, Claude P. Muller and Jonathan D. Turner

    Citation: Clinical Epigenetics 2016 8:12

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  11. Content type: Research

    DNA methylation profiles are responsive to environmental stimuli and metabolic shifts. This makes DNA methylation a potential biomarker of environmental-related and lifestyle-driven diseases of adulthood. Ther...

    Authors: Simonetta Guarrera, Giovanni Fiorito, N. Charlotte Onland-Moret, Alessia Russo, Claudia Agnoli, Alessandra Allione, Cornelia Di Gaetano, Amalia Mattiello, Fulvio Ricceri, Paolo Chiodini, Silvia Polidoro, Graziella Frasca, Monique W. M. Verschuren, Jolanda M. A. Boer, Licia Iacoviello, Yvonne T. van der Schouw…

    Citation: Clinical Epigenetics 2015 7:133

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