Lemmen JG, Pinborg A, Rasmussen S, Ziebe S. Birthweight distribution in ART singletons resulting from embryo culture in two different culture media compared with the national population. Hum Reprod (Oxford, England). 2014;29:2326–32.
Article
CAS
Google Scholar
Zhu L, Zhang Y, Liu Y, et al. Maternal and live-birth outcomes of pregnancies following assisted reproductive technology: a retrospective cohort study. Sci Rep. 2016;6:35141.
Article
PubMed
CAS
PubMed Central
Google Scholar
Romundstad LB, Romundstad PR, Sunde A, et al. Effects of technology or maternal factors on perinatal outcome after assisted fertilisation: a population-based cohort study. Lancet (London, England). 2008;372:737–43.
Article
PubMed
Google Scholar
Shapiro BS, Daneshmand ST, Bedient CE, Garner FC. Comparison of birth weights in patients randomly assigned to fresh or frozen-thawed embryo transfer. Fertil Steril. 2016;106:317–21.
Article
PubMed
Google Scholar
Maheshwari A, Pandey S, Shetty A, Hamilton M, Bhattacharya S. Obstetric and perinatal outcomes in singleton pregnancies resulting from the transfer of frozen thawed versus fresh embryos generated through in vitro fertilization treatment: a systematic review and meta-analysis. Fertil Steril 2012;98:368–77.e1–9.
Pinborg A, Loft A, Aaris Henningsen AK, Rasmussen S, Andersen AN. Infant outcome of 957 singletons born after frozen embryo replacement: the Danish National Cohort Study 1995–2006. Fertil Steril. 2010;94:1320–7.
Article
PubMed
Google Scholar
Berntsen S, Söderström-Anttila V, Wennerholm UB, et al. The health of children conceived by ART: The chicken or the egg? Hum Reprod Update. 2019;25:137–58.
Article
PubMed
Google Scholar
Westvik-Johari K, Romundstad LB, Lawlor DA, et al. Separating parental and treatment contributions to perinatal health after fresh and frozen embryo transfer in assisted reproduction: a cohort study with within-sibship analysis. PLoS Med. 2021;18: e1003683.
Article
PubMed
PubMed Central
Google Scholar
Castillo CM, Harper J, Roberts SA, O'Neill HC, Johnstone ED, Brison DR. The impact of selected embryo culture conditions on ART treatment cycle outcomes: a UK national study. Hum Reprod Open 2020;2020:hoz031.
Zheng Y, Dong X, Sui C, et al. Culture medium is associated with the risks of placenta previa and macrosomia in pregnancies after in vitro fertilization. Arch Gynecol Obstet 2022.
Morgan HD, Santos F, Green K, Dean W, Reik W. Epigenetic reprogramming in mammals. Hum Mol Genet 2005;14 Spec No 1:R47–58.
Mani S, Ghosh J, Coutifaris C, Sapienza C, Mainigi M. Epigenetic changes and assisted reproductive technologies. Epigenetics. 2020;15:12–25.
Article
PubMed
Google Scholar
Novakovic B, Lewis S, Halliday J, et al. Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood. Nat Commun. 2019;10:3922.
Article
PubMed
PubMed Central
Google Scholar
Melamed N, Choufani S, Wilkins-Haug LE, Koren G, Weksberg R. Comparison of genome-wide and gene-specific DNA methylation between ART and naturally conceived pregnancies. Epigenetics. 2015;10:474–83.
Article
PubMed
PubMed Central
Google Scholar
Katari S, Turan N, Bibikova M, et al. DNA methylation and gene expression differences in children conceived in vitro or in vivo. Hum Mol Genet. 2009;18:3769–78.
Article
PubMed
CAS
PubMed Central
Google Scholar
Håberg SE, Page CM, Lee Y, et al. DNA methylation in newborns conceived by assisted reproductive technology. Nat Commun. 2022;13:1896.
Article
PubMed
PubMed Central
Google Scholar
Caramaschi D, Jungius J, Page CM, et al. Association of medically assisted reproduction with offspring cord blood DNA methylation across cohorts. Hum Reprod (Oxford, England). 2021;36:2403–13.
Article
CAS
Google Scholar
Küpers LK, Monnereau C, Sharp GC, et al. Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight. Nat Commun. 2019;10:1893.
Article
PubMed
PubMed Central
Google Scholar
Bohlin J, Haberg SE, Magnus P, et al. Prediction of gestational age based on genome-wide differentially methylated regions. Genome Biol. 2016;17:207.
Article
PubMed
CAS
PubMed Central
Google Scholar
Merid SK, Novoloaca A, Sharp GC, et al. Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age. Genome Med. 2020;12:25.
Article
PubMed
CAS
PubMed Central
Google Scholar
Kupers LK, Xu X, Jankipersadsing SA, et al. DNA methylation mediates the effect of maternal smoking during pregnancy on birthweight of the offspring. Int J Epidemiol. 2015;44:1224–37.
Article
PubMed
PubMed Central
Google Scholar
Valeri L, Reese SL, Zhao S, et al. Misclassified exposure in epigenetic mediation analyses. Does DNA methylation mediate effects of smoking on birthweight? Epigenomics 2017;9:253–65.
Xu R, Hong X, Zhang B, et al. DNA methylation mediates the effect of maternal smoking on offspring birthweight: a birth cohort study of multi-ethnic US mother-newborn pairs. Clin Epigenet. 2021;13:47.
Article
Google Scholar
Magnus P, Irgens LM, Haug K, Nystad W, Skjaerven R, Stoltenberg C. Cohort profile: the Norwegian Mother and Child Cohort Study (MoBa). Int J Epidemiol. 2006;35:1146–50.
Article
PubMed
Google Scholar
Magnus P, Birke C, Vejrup K, et al. Cohort profile update: The Norwegian Mother and Child Cohort Study (MoBa). Int J Epidemiol. 2016;45:382–8.
Article
PubMed
Google Scholar
Ronningen KS, Paltiel L, Meltzer HM, et al. The biobank of the Norwegian Mother and Child Cohort Study: a resource for the next 100 years. Eur J Epidemiol. 2006;21:619–25.
Article
PubMed
CAS
PubMed Central
Google Scholar
Paltiel L, Anita H, Skjerden T, et al. The biobank of the Norwegian Mother and Child Cohort Study—present status. Norsk Epidemiologi 2014;24.
Pidsley R, Zotenko E, Peters TJ, et al. Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling. Genome Biol. 2016;17:208.
Article
PubMed
PubMed Central
Google Scholar
Muller F, Scherer M, Assenov Y, et al. RnBeads 2.0: comprehensive analysis of DNA methylation data. Genome Biol 2019;20:55.
McCartney DL, Walker RM, Morris SW, McIntosh AM, Porteous DJ, Evans KL. Identification of polymorphic and off-target probe binding sites on the Illumina Infinium MethylationEPIC BeadChip. Genom Data. 2016;9:22–4.
Article
PubMed
PubMed Central
Google Scholar
Ziller MJ, Gu H, Müller F, et al. Charting a dynamic DNA methylation landscape of the human genome. Nature. 2013;500:477–81.
Article
PubMed
CAS
PubMed Central
Google Scholar
Pidsley R, CC YW, Volta M, Lunnon K, Mill J, Schalkwyk LC. A data-driven approach to preprocessing Illumina 450K methylation array data. BMC Genom 2013;14:293.
Markunas CA, Wilcox AJ, Xu Z, et al. Maternal age at delivery is associated with an epigenetic signature in both newborns and adults. PLoS ONE. 2016;11: e0156361.
Article
PubMed
PubMed Central
Google Scholar
Joubert BR, Felix JF, Yousefi P, et al. DNA methylation in newborns and maternal smoking in pregnancy: genome-wide consortium meta-analysis. Am J Hum Genet. 2016;98:680–96.
Article
PubMed
CAS
PubMed Central
Google Scholar
Sharp GC, Salas LA, Monnereau C, et al. Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium. Hum Mol Genet. 2017;26:4067–85.
Article
PubMed
CAS
PubMed Central
Google Scholar
Alfano R, Guida F, Galobardes B, et al. Socioeconomic position during pregnancy and DNA methylation signatures at three stages across early life: epigenome-wide association studies in the ALSPAC birth cohort. Int J Epidemiol. 2019;48:30–44.
Article
PubMed
Google Scholar
Hinkle SN, Albert PS, Mendola P, et al. The association between parity and birthweight in a longitudinal consecutive pregnancy cohort. Paediatr Perinat Epidemiol. 2014;28:106–15.
Article
PubMed
Google Scholar
Yousefi P, Huen K, Dave V, Barcellos L, Eskenazi B, Holland N. Sex differences in DNA methylation assessed by 450 K BeadChip in newborns. BMC Genom. 2015;16:911.
Article
Google Scholar
Joubert BR, den Dekker HT, Felix JF, et al. Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns. Nat Commun. 2016;7:10577.
Article
PubMed
CAS
PubMed Central
Google Scholar
Fekete K, Berti C, Trovato M, et al. Effect of folate intake on health outcomes in pregnancy: a systematic review and meta-analysis on birth weight, placental weight and length of gestation. Nutr J. 2012;11:75.
Article
PubMed
CAS
PubMed Central
Google Scholar
Grieger JA, Clifton VL. A review of the impact of dietary intakes in human pregnancy on infant birthweight. Nutrients. 2014;7:153–78.
Article
PubMed
PubMed Central
Google Scholar
Wilcox AJ, Weinberg CR, Basso O. On the pitfalls of adjusting for gestational age at birth. Am J Epidemiol. 2011;174:1062–8.
Article
PubMed
PubMed Central
Google Scholar
Cole SR, Platt RW, Schisterman EF, et al. Illustrating bias due to conditioning on a collider. Int J Epidemiol. 2010;39:417–20.
Article
PubMed
Google Scholar
Du P, Zhang X, Huang CC, et al. Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis. BMC Bioinf. 2010;11:587.
Article
CAS
Google Scholar
Baron RM, Kenny DA. The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J Pers Soc Psychol. 1986;51:1173–82.
Article
PubMed
CAS
Google Scholar
Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Ser B (Methodol). 1995;57:289–300.
Google Scholar
Haftorn KL, Lee Y, Denault WRP, et al. An EPIC predictor of gestational age and its application to newborns conceived by assisted reproductive technologies. Clin Epigenet. 2021;13:82.
Article
CAS
Google Scholar
van Iterson M, van Zwet EW, Heijmans BT. Controlling bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution. Genome Biol. 2017;18:19.
Article
PubMed
PubMed Central
Google Scholar
Valeri L, Vanderweele TJ. Mediation analysis allowing for exposure-mediator interactions and causal interpretation: theoretical assumptions and implementation with SAS and SPSS macros. Psychol Methods. 2013;18:137–50.
Article
PubMed
PubMed Central
Google Scholar
Jiang Z, VanderWeele TJ. When is the difference method conservative for assessing mediation? Am J Epidemiol. 2015;182:105–8.
Article
PubMed
PubMed Central
Google Scholar
Håberg S, Page CM, Lee Y, et al. DNA methylation in newborns conceived by assisted reproductive technology. Nat Commun In press.
Polettini J, Silva MG, Kacerovsky M, Syed TA, Saade GR, Menon R. Screening of lysyl oxidase (LOX) and lysyl oxidase like (LOXL) enzyme expression and activity in preterm prelabor rupture of fetal membranes. J Perinat Med. 2016;44:99–109.
PubMed
CAS
Google Scholar
Wang YW, Wang WS, Wang LY, et al. Extracellular matrix remodeling effects of serum amyloid A1 in the human amnion: implications for fetal membrane rupture. Am J Reprod Immunol (New York, NY : 1989) 2019;81:e13073.
Matsunaga E, Nambu S, Oka M, Iriki A. Complex and dynamic expression of cadherins in the embryonic marmoset cerebral cortex. Dev Growth Differ. 2015;57:474–83.
Article
PubMed
CAS
PubMed Central
Google Scholar
Kuwako KI, Nishimoto Y, Kawase S, Okano HJ, Okano H. Cadherin-7 regulates mossy fiber connectivity in the cerebellum. Cell Rep. 2014;9:311–23.
Article
PubMed
CAS
Google Scholar
Matsunaga E, Kurotani T, Suzuki K, Okanoya K. Type-II cadherins modulate neural activity in cultured rat hippocampal neurons. NeuroReport. 2011;22:629–32.
Article
PubMed
CAS
Google Scholar
Djuwantono T, Aviani JK, Permadi W, Achmad TH, Halim D. Risk of neurodevelopmental disorders in children born from different ART treatments: a systematic review and meta-analysis. J Neurodev Disord. 2020;12:33.
Article
PubMed
PubMed Central
Google Scholar
Montes MJ, Alemán P, García-Tortosa C, Borja C, Ruiz C, García-Olivares E. Cultured human decidual stromal cells express antigens associated with hematopoietic cells. J Reprod Immunol. 1996;30:53–66.
Article
PubMed
CAS
Google Scholar
Oliver C, Cowdrey N, Abadía-Molina AC, Olivares EG. Antigen phenotype of cultured decidual stromal cells of human term decidua. J Reprod Immunol. 1999;45:19–30.
Article
PubMed
CAS
Google Scholar
Ding D, Liu J, Dong K, et al. PNLDC1 is essential for piRNA 3’ end trimming and transposon silencing during spermatogenesis in mice. Nat Commun. 2017;8:819.
Article
PubMed
PubMed Central
Google Scholar
Dai X, Cheng X, Huang J, et al. Rbm46, a novel germ cell-specific factor, modulates meiotic progression and spermatogenesis. Biol Reprod. 2021;104:1139–53.
Article
PubMed
Google Scholar
Anastasakis D, Skeparnias I, Shaukat AN, et al. Mammalian PNLDC1 is a novel poly(A) specific exonuclease with discrete expression during early development. Nucleic Acids Res. 2016;44:8908–20.
Article
PubMed
CAS
PubMed Central
Google Scholar
Fagerberg L, Hallström BM, Oksvold P, et al. Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. Mol Cell Proteom. 2014;13:397–406.
Article
CAS
Google Scholar
Mustafin RN, Kazantseva AV, Enikeeva RF, Malykh SB, Khusnutdinova EK. Longitudinal genetic studies of cognitive characteristics. Vavilovskii Zhurnal Genet Selektsii. 2020;24:87–95.
PubMed
CAS
PubMed Central
Google Scholar
Gauthier KD, Rocheleau CE. Golgi localization of the LIN-2/7/10 complex points to a role in basolateral secretion of LET-23 EGFR in the Caenorhabditis elegans vulval precursor cells. Development 2021;148.
Dinchuk JE, Car BD, Focht RJ, et al. Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II. Nature. 1995;378:406–9.
Article
PubMed
CAS
Google Scholar
Lim H, Paria BC, Das SK, et al. Multiple female reproductive failures in cyclooxygenase 2-deficient mice. Cell. 1997;91:197–208.
Article
PubMed
CAS
Google Scholar
Langenbach R, Morham SG, Tiano HF, et al. Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. Cell. 1995;83:483–92.
Article
PubMed
CAS
Google Scholar
Reese J, Paria BC, Brown N, Zhao X, Morrow JD, Dey SK. Coordinated regulation of fetal and maternal prostaglandins directs successful birth and postnatal adaptation in the mouse. Proc Natl Acad Sci USA. 2000;97:9759–64.
Article
PubMed
CAS
PubMed Central
Google Scholar
Watanabe-Okochi N, Oki T, Komeno Y, et al. Possible involvement of RasGRP4 in leukemogenesis. Int J Hematol. 2009;89:470–81.
Article
PubMed
CAS
Google Scholar
Zhu L, Xia C, Wu L, et al. The critical role of RasGRP4 in the growth of diffuse large B cell lymphoma. Cell Commun Signal. 2019;17:92.
Article
PubMed
PubMed Central
Google Scholar
Reuther GW, Lambert QT, Rebhun JF, Caligiuri MA, Quilliam LA, Der CJ. RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia. J Biol Chem. 2002;277:30508–14.
Article
PubMed
CAS
Google Scholar
Samuelsen SO, Bakketeig LS, Tretli S, Johannesen TB, Magnus P. Brief Report: Birth Weight and Childhood Cancer. Epidemiology 2009:484–7.
Hargreave M, Jensen A, Hansen MK, et al. Association between fertility treatment and cancer risk in children. JAMA. 2019;322:2203–10.
Article
PubMed
PubMed Central
Google Scholar
Magnus MC, Wilcox AJ, Fadum EA, et al. Growth in children conceived by ART. Hum Reprod (Oxford, England). 2021;36:1074–82.
Article
Google Scholar
Samuelsen SO, Bakketeig LS, Tretli S, Johannesen TB, Magnus P. Head circumference at birth and risk of brain cancer in childhood: a population-based study. Lancet Oncol. 2006;7:39–42.
Article
PubMed
Google Scholar
Samuelsen SO, Bakketeig LS, Tretli S, Johannesen TB, Magnus P. Birth weight and childhood cancer. Epidemiology. 2009;20:484–7.
Article
PubMed
Google Scholar
Nilsen RM, Vollset SE, Gjessing HK, et al. Self-selection and bias in a large prospective pregnancy cohort in Norway. Paediatr Perinat Epidemiol. 2009;23:597–608.
Article
PubMed
Google Scholar
Goisis A, Håberg SE, Hanevik HI, Magnus MC, Kravdal Ø. The demographics of assisted reproductive technology births in a Nordic country. Hum Reprodu (Oxford, England). 2020;35:1441–50.
Article
Google Scholar
Richiardi L, Bellocco R, Zugna D. Mediation analysis in epidemiology: methods, interpretation and bias. Int J Epidemiol. 2013;42:1511–9.
Article
PubMed
Google Scholar
Kazmi N, Sharp GC, Reese SE, et al. Hypertensive disorders of pregnancy and DNA methylation in newborns. Hypertension. 2019;74:375–83.
Article
PubMed
CAS
Google Scholar
Kiserud T, Benachi A, Hecher K, et al. The World Health Organization fetal growth charts: concept, findings, interpretation, and application. Am J Obstet Gynecol. 2018;218:S619–29.
Article
PubMed
Google Scholar
Penova-Veselinovic B, Melton PE, Huang RC, et al. DNA methylation patterns within whole blood of adolescents born from assisted reproductive technology are not different from adolescents born from natural conception. Hum Reprod (Oxford, England). 2021;36:2035–49.
Article
CAS
Google Scholar