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Regenerative medicine

Section information

Section Editor: Adele Murrell
Associate Editor: Peter Rugg-Gunn

Regenerative medicine seeks to repair or replace damaged or diseased human cells or tissues to restore normal function. It may involve the transplantation of stem cells, progenitor cells or tissue, stimulation of the body's own repair processes. All regenerative medicine strategies depend upon the harnessing, stimulation or guidance of endogenous developmental or repair processes, with stem cell biology at the core. We invite research papers on the epigenetic processes involved in stem cell maintenance, reprogramming, differentiation and transdifferentiation with evidence of clinical impact for regenerative medicine on disease. Cell culture systems have in recent years evolved from monolayer cultures to 3-dimentional spheroids and organoids which are reported to be epigenetically more similar to the parental tissue.  We also therefore welcome field-advancing methodology reports for cell based developments that take into consideration the impact of such manipulations on epigenetic stability.