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Table 1 Patient demographics, clinical, and peri-operative characteristics

From: Serum level of total histone 3, H3K4me3, and H3K27ac after non-emergent cardiac surgery suggests the persistence of smoldering inflammation at 3 months in an adult population

Patient demographics

(N = 59)

Age (X ± SD [years])

65.1 ± 11.16

Age above 60 [(% of total])

 

Males (n [% of total])

39 (66.1%)

BMI (X ± SD [kg/m2])

2.2 ± 0.89

Race (% of total)

 

 Caucasian

84.7%

 Black

5.1%

 Asian

5.1%

 Other

5.1%

Anesthesia and surgery data

 

Duration of anesthesia (mean ± SD [min])

370.3 ± 91.72

Duration of surgery (mean ± SD [min])

257.8 ± 76.82

Coronary artery bypass surgery (n)

31

Extracorporeal circulation (% of total; duration [X ± SD (min)]

89%; 127.6 ± 58.2

Aortic-cross-clamp (% of total; duration [X ± SD (min)]

86%; 87.9 ± 43.9

Mitral valvuloplasty and replacement (n)

10

Aortic valvuloplasty and replacement (n)

20

Aortic aneurysm repair (n)

7

Others (n)

4

Estimated Blood Loss (X ± SD [mL])

180.7 ± 216.39

Peri-operative management

 

 Transfusions during surgery

 

Packed Red Blood Cells (mean [CI 95%] [mL])

94.8 (0;1200)

Fresh Frozen Plasma (mean [CI 95%] [mL])

48.2 (0;750)

Cell Server (mean [CI 95%] [mL])

640.8 (0;1350)

Total crystalloid during surgery (X ± SD [mL])

1365.7 ± 544.08

 Clinical Care 24 h post-surgery

 

Packed Red Blood Cells (mean [CI 95%] [mL])

21 (0;600)

Fresh Frozen Plasma (mean [CI 95%] [mL])

0 (0;0)

Corticosteroid Administration (% of total)

10.2%

Ketorolac Administration (% of total)

3.4%

Acetaminophen Administration (% of total)

79.7%

ASA Administration (% of total)

72.9%

APACHE scores during ICU stay (X ± SD)

 

1 h

18.6 ± 5.96

24 h

10.2 ± 5.72

48 h

9.9 ± 5.57

Comorbidities

(% of total)

CCI (median [95% CI])

4(1.6;2.4)

Acute Coronary Syndrome

15.25%

Chronic heart failure

15.25%

Connective tissue disease (non-active)

5.7%

Cerebrovascular disease

10.2%

Type 2 diabetes

37.3%

AIDS

1.6%

COPD

8.47%

Leukemia/neoplasms

0%

Acquired Immunodeficiency Syndrome

0%

Outcomes

 

Mortality

5.08%

  1. SD = standard deviation; BMI = body mass index; CI = confidence interval; ASA = ; APACHE = acute physiological assessment and chronic health evaluation; CCI = Charlson Comorbidity Index; AIDS = acquired immunodeficiency syndrome; COPD = chronic obstructive pulmonary disease