Fig. 19
From: Epigenetic tumor heterogeneity in the era of single-cell profiling with nanopore sequencing
Direct reading of DNA methylation by nanopore sequencing. The ionic current is changed as single-stranded DNA passes through the pore; having a methyl group and small changes due to methylation are interpreted by a new set of algorithms. Image reprinted from [25] with permission of the publisher (Request ID: 600061678, 27 Nov 2021)