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Table 2 Results from the differential methylation analyses, comparing the active treatments vs. the double placebo group

From: Combined prenatal Lactobacillus reuteri and ω-3 supplementation synergistically modulates DNA methylation in neonatal T helper cells

Intervention group vs. PP LP vs. PP vs. PP
DMCs 1 659 1246 984
Hypomethylated CpGs 576 (35%) 380 (30%) 415 (42%)
Hypermethylated CpGs 1083 (65%) 866 (70%) 569 (58%)
DMGs 794 620 494
Hypomethylated genes 247 (31%) 204 (33%) 184 (37%)
Hypermethylated genes 524 (66%) 405 (65%) 295 (60%)
Mixed methylation genes 23 (3%) 11 (2%) 15 (3%)
  1. Proportions of hypo- and hypermethylated CpGs and genes, from the differential DNA methylation analyses comparing the active treatment groups vs. the double placebo group, are presented as n (% of total). DMCs—differentially methylated CpGs, DMGs—differentially methylated genes, L—Lactobacillus reuteri, ω—ω-3 fatty acids, P—placebo