Fig. 5
![Fig. 5](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13148-021-01115-4/MediaObjects/13148_2021_1115_Fig5_HTML.png)
River plots illustrating the methylation status for overlapping genes being shared between the double-treated Lω group and A the single-treated probiotic (LP vs. PP), and B ω-3 treated (Pω vs. PP) group. Panel C illustrates comparisons between the single treated groups (LP and Pω vs. PP) and D shows the comparison between all treatment groups. Genes are represented as flows of size proportional to number of genes within their methylation status in a particular set, and differences between sets are shown as connections between flows. The respective gene names are denoted next to each flow. Red represents hypermethylation, blue hypomethylation and green a mixed methylation pattern. The number of genes in the respective flows are denoted in the graph. L—Lactobacillus reuteri, ω—ω-3 fatty acids, P—placebo