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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Epigenetic modulators as therapeutic targets in prostate cancer

Fig. 1

Epigenetic alterations involved in PCa development and progression. Several epigenetic aberrations, as silencing of tumor suppressor genes by promoter hypermethylation, aberrant expression of histone modulating proteins, and DNA hypomethylation contribute not only to PCa onset but also to its progression to advanced and castration-resistant cancer

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