Open Access

Erratum to: The integrative epigenomic-transcriptomic landscape of ER positive breast cancer

  • Yang Gao1,
  • Allison Jones2,
  • Peter A. Fasching3,
  • Matthias Ruebner3,
  • Matthias W. Beckmann3,
  • Martin Widschwendter2 and
  • Andrew E. Teschendorff1, 2, 4Email author
Clinical EpigeneticsThe official journal of the Clinical Epigenetics Society20168:63

https://doi.org/10.1186/s13148-016-0231-4

Received: 25 May 2016

Accepted: 25 May 2016

Published: 1 June 2016

The original article was published in Clinical Epigenetics 2015 7:126

Erratum

Unfortunately, after publication of the original version of this article [1], we noticed an error in Figure S8 in Additional file 1. Specifically, the error relates to the legend of the figure, as what is being diplayed in this figure is not the shortest path between pairs of top ranked features, but the smallest number of path links one needs to remove in order for the pair of features to be disconnected. Unfortunately, this completely alters the corresponding statement in the last paragraph of the Results section, since the smaller average path link number for DNA methylation, as shown in Figure S8, means that in effect top ranked DNA methylation alterations occur more distantly apart on the network than top-ranked copy-number alterations. This does not however alter the conclusion about DNA methylation exhibit coordinated changes across samples, as shown in Fig. 6, since the analysis presented in Figure S8 does not consider alterations in individual samples, whereas the data shown in Fig. 6 does. Hence, the main conclusion that DNA methylation alterations in FEM modules exhibit coordination modularity is unaffected. However, top-ranked DNA methylation alterations map further apart on the network than corresponding copy-number alterations.

Notes

Declarations

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Authors’ Affiliations

(1)
CAS Key Lab for Computational Biology, CAS-MPG Partner Institute for Computational Biology, Chinese Academy of Sciences, Shanghai Institute for Biological Sciences
(2)
Department of Women’s Cancer, University College London
(3)
Department of Gynaecology and Obstetrics, Friedrich-Alexander University Erlangen-Nuremberg, University Clinic Erlangen
(4)
Statistical Genomics Group, Paul O’Gorman Building, UCL Cancer Institute, University College London

References

  1. Gao Y, Jones A, Fasching PA, Ruebner M, Beckmann MW, Widschwendter M, et al. The integrative epigenomic-transcriptomic landscape of ER positive breast cancer. Clin Epigenetics. 2015;7:126. doi:https://doi.org/10.1186/s13148-015-0159-0.View ArticlePubMedPubMed CentralGoogle Scholar

Copyright

© The Author(s). 2016

Advertisement