Open Access

Erratum to: Imprinting disorders: a group of congenital disorders with overlapping patterns of molecular changes affecting imprinted loci

  • Thomas Eggermann1, 13, 14Email author,
  • Guiomar Perez de Nanclares2,
  • Eamonn R. Maher3,
  • I. Karen Temple4, 5,
  • Zeynep Tümer6,
  • David Monk7,
  • Deborah J. G. Mackay4, 5,
  • Karen Grønskov6,
  • Andrea Riccio8,
  • Agnès Linglart9 and
  • Irène Netchine10, 11, 12
Clinical EpigeneticsThe official journal of the Clinical Epigenetics Society20168:27

Received: 1 March 2016

Accepted: 1 March 2016

Published: 7 March 2016

The original article was published in Clinical Epigenetics 2015 7:123


Unfortunately, after publication of the original version of this article [1], it was noticed that there were some errors in Fig. 3 and Fig. 4:
  • In Fig. 3, the methylation of H19/IGF2:IG-DMR hypomethylation is not correctly illustrated: the lolly pops should be empty (=unmethylated).

  • In Fig. 4, the methylation of both H19/IGF2:IG-DMR hypermethylation and KCNQ1OT1:TSS-DMR hypomethylation are not correctly illustrated: in case of the H19/IGF2:IG-DMR hypermethylation the lolly pops should be filled (=methylated), and for the KCNQ1OT1:TSS-DMR, they should be empty (=unmethylated).

The corrected Fig. 3 and Fig. 4 have been included in this erratum.
Fig. 3

The 11p15.5 cluster can be divided in two functional domains whose imprinting is dependent on distinct imprinting control regions (H19/IGF2: IG DMR and KCNQ1OT1: TSS DMR). Mainly hypomethylation of the KCNQ1OT1: TSS DMR is responsible for SRS

Fig. 4

Epimutations and mutations in 11p15.5 are also responsible for BWS



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Authors’ Affiliations

Department of Human Genetics, RWTH Aachen
Molecular (Epi)Genetics Laboratory, BioAraba National Health Institute
Department of Medical Genetics, University of Cambridge and NIHR Cambridge Biomedical Research Centre
Human Genetics and Genomic Medicine, Faculty of Medicine University of Southampton
WessexClinical Genetics Service, Princess Anne Hospital
Clinical Genetic Clinic, Kennedy Center, Rigshospitalet, Copenhagen University Hospital
Imprinting and Cancer Group, Cancer Epigenetic and Biology Program (PEBC), Institut d’Investigació Biomedica de Bellvitge (IDIBELL)
DiSTABiF, Seconda Università degli Studi di Napoli
Institute of Genetics and Biophysics—ABT, CNR
Endocrinology and diabetology for children and reference center for rare disorders of calcium and phosphorus metabolism
Sorbonne Universites, UPMC Univ Paris 06, UMR_S 938
3APHP, Pediatric Endocrinology


  1. Eggermann T, Perez de Nanclares G, Maher ER, Temple IK, Tümer Z, Monk D, et al. Imprinting disorders: a group of congenital disorders with overlapping patterns of molecular changes affecting imprinted loci. Clin Epigenetics. 2015;7:123. doi:10.1186/s13148-015-0143-8.View ArticlePubMedPubMed CentralGoogle Scholar


© Eggermann et al. 2016