Insulin resistance is associated with epigenetic and genetic regulation of mitochondrial DNA in obese humans

Clinical Epigenetics

Table 2 Univariate regression analysis of mtDNAn among all subjects

Parameters	β coefficient	R value	p value
Age	−0.008	0.212	0.189
BMI	−0.026	0.333	0.041
Fasting glucose	−0.004	0.084	0.604
Fasting insulin	−0.015	0.320	0.044
HOMA-IR	−0.703	0.379	0.016
Triglyceride	−0.001	0.163	0.314
HDL	0.010	0.187	0.248
LDL	−0.002	0.095	0.569
VLDL	−0.005	0.165	0.310
LDL/HDL ratio	−0.130	0.133	0.425
Total cholesterol	−0.001	0.050	0.760
Cholesterol/HDL	−0.116	0.178	0.272
HbA1c	0.182	0.115	0.480

ISSN: 1868-7083