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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Discovery and technical validation of high-performance methylated DNA markers for the detection of cervical lesions at risk of malignant progression in low- and middle-income countries

Fig. 6

Human papilloma virus (HPV)-positive and HPV-negative cervical carcinomas are highly methylated for the 5-marker panel. Histograms and box plots of Cumulative β Methylation in the 5-marker panel in HPV-positive and HPV-negative carcinomas in (A). The Cancer Genome Atlas-Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA-CESC) and Uterine Corpus Endometrial Carcinoma (UCEC) datasets; 17/307 primary tumors were HPV-negative; B The Genomic Spatial Event (GSE) GSE68339 database; 20/268 SCC were HPV-negative

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