Evaluating the link between DIO3-FA27 promoter methylation, biochemical indices, and heart failure progression

Clinical Epigenetics

Table 2 Comparison of biochemical indices with different cardiac functions \(({\bar{x}\pm{\text{SD}}})\)

Biochemical Indices	I/II (n = 10)	III/IV (n = 10)	P-value
PTA (sec.)	2.60 ± 1.35	1.70 ± 0.95	0.10
PTR (sec.)	2.10 ± 1.29	3.40 ± 0.97	0.02
APTT (sec.)	2.90 ± 1.20	2.90 ± 1.37	1.00
FDP (mg/L)	1.80 ± 1.14	2.60 ± 1.35	0.17
TG (mmol/L)	1.80 ± 1.03	1.90 ± 0.99	0.83
TC(mmol/L)	2.40 ± 1.43	2.0 ± 1.15	0.50
HDL (mmol/L)	3.50 ± 0.53	2.90 ± 1.10	0.14
ApoA-1 (g/L)	3.60 ± 0.51	2.40 ± 0.84	0.01
LDL (mmol/L)	3.30 ± 0.67	2.60 ± 0.96	0.08
ApoB (g/L)	3.30 ± 0.67	2.60 ± 0.97	0.08
MCV (fL)	2.40 ± 0.97	1.50 ± 0.97	0.05
MCH (pg)	2.50 ± 1.08	1.70 ± 0.95	0.09
CHE (μ/L)	2.50 ± 0.97	2.10 ± 0.99	0.38
Urea (mmol/L)	2.10 ± 1.20	3.10 ± 1.20	0.08
ALP (μ/L)	1.70 ± 0.67	2.10 ± 1.10	0.34
IBIL (μmol/L)	2.90 ± 1.1	2.3 ± 1.50	0.32

PTA prothrombin time activity, PTR prothrombin time ratio, APTT activated partial thromboplastin time, FDP fibrin degradation products, TG triglyceride; TC serum total cholesterol; HDL high-density lipoprotein; ApoA-1 apolipoprotein A-I, LDL high-density lipoprotein, ApoB apolipoprotein B; MCV mean volume of red blood cells, MCH mean corpuscular hemoglobin, CHE cholinesterase; ALP alkaline phosphatase, IBIL indirect bilirubin

ISSN: 1868-7083