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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Mother adversity and co-residence time impact mother–child similarity in genome-wide and gene-specific methylation profiles

Fig. 3

Linear regression shows the influence of the covariates of interest on the Methylation Similarity Index (MSI) in the genome-wide analyses. A Higher levels of Mother adversity were significantly associated with a lower MSI, whereas older Child age was significantly associated with a higher MSI. The length of the bar indicates the t-statistic value corresponding to each regression coefficient. The red asterisks denote statistical significance after multiple comparison corrections. B The scatter plot illustrates the effects of the Mother adversity on MSI. C The scatter plot shows the influence of the Child age on MSI. Every dot in the plot corresponds to a mother–child dyad when MSI was computed with all CpGs. Note that for each of the scatter plots, the contribution of the other significant variables in the model was removed from the MSI and the resulting residuals were used for visualization purpose

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Clinical Epigenetics

ISSN: 1868-7083

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