Fig. 3

Differentially methylated genes in irradiated HAECs and HCAECs. Heat map and hierarchical clustering dendrogram of differential gene methylation profiles from irradiated A HAECs and B HCAECs. C, D A Venn diagram illustrates the number of hypomethylated and hypermethylated CpG sites identified among four distinct radiation doses, including a low dose. E, F GO analysis of genes associated with differentially methylated CpGs in HAECs exposed to low-dose radiation (0.1 Gy). The GO analysis was performed using Metascape, based on the genes derived from differentially methylated CpGs in E HAECs or F HCAECs irradiated with low-dose radiation (0.1 Gy) compared to controls