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Fig. 7 | Clinical Epigenetics

Fig. 7

From: Exploring the therapeutic potential of Sirt6-enriched adipose stem cell-derived exosomes in myocardial ischemia–reperfusion injury: unfolding new epigenetic frontiers

Fig. 7

Ultrastructural and histologic examinations, and protein expressions in ischemic myocardia. A Representative TEM pictures, HE staining, and Masson staining sections of myocardial tissue. Green arrows indicating cell membrane lysis in the control group and typical mitophagy in the S-ASC-Exo group. For Masson staining, green arrows indicating fibrosis. B Representative western blot pictures showing expressions of Sirt6, AIM2, GSDMD, p62, and Beclin-1 in myocardial tissues. C–G Densitometric quantification of Sirt6 (P = 0.003), AIM2 (P = 0.041), GSDMD (P = 0.005), p62 (P = 0.004), and Beclin-1 (P < 0.001) expressions: sham (n = 6), control (n = 6), and S-ASC-Exo (n = 6) groups. *P < 0.05, versus control. Scale bar = 100 mm

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Clinical Epigenetics

ISSN: 1868-7083

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