Fig. 3

S-ASC-Exo inhibits AIM2-pyroptosis and promotes mitophagy in H9c2s subjected to AR. A LDH measured by ELSIA (P = 0.015). B Cell viability measured by MTT (P = 0.021). C Representative western blot pictures showing expressions of AIM2, GSDMD, p62, and Beclin-1. D mRNA levels of AIM2 (P = 0.018), GSDMD (P = 0.016), p62 (P = 0.004), and Beclin-1 (P = 0.007). E Densitometric quantification of AIM2 (P = 0.042), GSDMD (P = 0.045), p62 (P < 0.001), and Beclin-1 (P = 0.003) expressions. *P < 0.05, versus control