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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Exploring the therapeutic potential of Sirt6-enriched adipose stem cell-derived exosomes in myocardial ischemia–reperfusion injury: unfolding new epigenetic frontiers

Fig. 2

Exosome characterization and transfection efficiency. A ASCs transfected with pre-Sirt6 (green fluorescence). TEM image of exosome. Representative western blot pictures showing positive expressions of CD9, CD63, and CD81, while negative expression of Calnexin. B Representative image of PHK67-labeled exosomes (green) and Phalloidin (red) double-immunostaining in H9c2s. C Representative western blot pictures showing Sirt6 expressions. D–F Densitometric quantification of Sirt6 expression levels in transfected groups versus un-transfected groups. *P < 0.05. S-ASC, ASCs transfected with pre-Sirt6; ASC-Exo, exosomes from ASCs; S-ASC-Exo, exosomes from S-ASCs; S-Exo-H9c2, H9c2s engulfing S-ASC-Exo

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Clinical Epigenetics

ISSN: 1868-7083

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