Fig. 2From: Unlocking the secrets: the power of methylation-based cfDNA detection of tissue damage in organ systemsDNA methylation and demethylation mechanisms in organ and tissue damage. Tissue and organ damage can regulate DNMTs and DNA demethylases (e.g., TET and TDG) through various mechanisms, thereby influencing the state of DNA methylation, including inflammation, oxidative stress, and DNA damage repair mechanismsBack to article page