Fig. 7
From: Loss of H3K27 methylation identifies poor outcomes in adult-onset acute leukemia
a Overall survival (OS) between Ph+ ALL patients treated with TKIs (green) and those who were diagnosed with Ph+ ALL before TKI implementation (blue). b Relative RPPA levels of H3K4me2 (left), H3K4me3 (middle) and H3K27me3 (right) of TKI treated Ph+ ALL patients (n = 11) according to 5-years survivors (Resp = responder alive after 5-years follow-up, non-Resp = non-responder who passed away within 5 years of follow-up). Significant lower H3K4me2 and H3K4me3 was observed in non-responders compared to responders