Gene name | CpG site/s | P value/FDR cutoff | Methylation and transcript status by pyrosequencing and qPCR | Correlation coefficient (R2); P value |
---|---|---|---|---|
AKR1C3 | CpG-880 | <  0.05 | Hypomethylated upregulated | − 0.53; 0.02* |
CASR | CpG-680 | <  0.05 | Hypomethylated upregulated | − 0.74; <  0.0001* |
GHRHR | CpG-809 | <  0.025 | Hypomethylated upregulated | − 0.669; 0.002* |
CpG-721 | − 0.501; 0.034 | |||
RETN | CpG-177 | <  0.05 | Hypomethylated upregulated | − 0.603; 0.029* |
MAMLD1 | CpG-129 | <  0.016 | Hypomethylated upregulated | − 0.759; <  0.0001* |
CpG-116 | − 0.596; 0.007* | |||
CpG-113 | − 0.612; 0.005* | |||
TNF | CpG-242 | <  0.025 | Hypermethylated downregulated | − 0.582; 0.011* |
TF | CpG-358 | <  0.05 | Hypomethylated downregulated | − 0.162; 0.507 |