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Fig. 4 | Clinical Epigenetics

Fig. 4

From: CpG location and methylation level are crucial factors for the early detection of oral squamous cell carcinoma in brushing samples using bisulfite sequencing of a 13-gene panel

Fig. 4

Methylation profile plot from GP1BB and ZAP70. For each group of samples, each line represents the methylation mean for each position. Asterisks indicate a statistical significance as calculated by the Kruskal-Wallis test. ZAP70 and GP1BB, together with H19, EPHX3, and MIR193 (see Additional file 1 for the methylation profile of all targets), revealed a fluctuating behavior among the various CpGs evaluated. The gap between normal and OSCC remained mostly the same (Kruskal-Wallis P values were < 0.05), but the absolute values changed conspicuously among different positions investigated

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Clinical Epigenetics

ISSN: 1868-7083

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