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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Cooperative effect of chidamide and chemotherapeutic drugs induce apoptosis by DNA damage accumulation and repair defects in acute myeloid leukemia stem and progenitor cells

Fig. 3

Chidamide intensified IDA-induced cell cycle arrest in CD34+CD38 KG1α cells. (a) CD34+CD38 KG1α cells were exposed to 5 or 10 nM IDA with or without 0.5 or 0.75 μM chidamide for 72 h, after which flow cytometric analysis was performed to determine the cell cycle. Horizontal lines represented the mean ± S.D. from three independent experiments. (b) Representative data for flow cytometric analysis of PI staining in CD34+CD38 KG1α cells after exposed (72 h) to 5 or 10 nM IDA with or without 0.5 or 0.75 μM chidamide

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