From: DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD
Smokers vs. non-smokers | ||
Canonical pathways | P value | Overlap |
B cell development | 1.25E-02 | 3.0% 1/33 |
Antigen presentation pathway | 1.40E-02 | 2.7% 1/37 |
Autoimmune thyroid disease signaling | 1.77E-02 | 2.1% 1/47 |
Graft-vs.-host disease signaling | 1.81E-02 | 2.1% 1/48 |
Nur77 signaling in T lymphocytes | 2.15E-02 | 1.8% 1/57 |
COPD vs. non-smokers | ||
Canonical pathways | P value | Overlap |
G Beta gamma signaling | 5.35E-06 | 8.1% 7/86 |
GNRH signaling | 6.42E-06 | 6.5% 8/124 |
Molecular mechanisms of cancer | 6.98E-06 | 3.6% 13/366 |
Role of NFAT in cardiac hypertrophy | 1.82E-05 | 4.8% 9/187 |
nNOS signaling in neurons | 2.74E-05 | 11.1% 5/45 |