Cohort | Group | Males | Females | P valuesa | ||
---|---|---|---|---|---|---|
Number of placentas | Global methylation fraction (mean ± SD) | Number of placentas | Global methylation fraction (mean ± SD) | |||
Original cohort | Controls | 33 | 0.5091 ± 0.0463 | 32 | 0.4902 ± 0.0448 | 0.0494 |
ART | 56 | 0.4785 ± 0.0402 | 70 | 0.4791 ± 0.0503 | 0.4727 | |
Validation cohort | Controls | 29 | 0.4266 ± 0.0401 | 28 | 0.3936 ± 0.0583 | 0.0078 |
ART | 26 | 0.4227 ± 0.0382 | 29 | 0.4386 ± 0.09538 | 0.2149 | |
Opposite sex twins | ART | 39 | 0.4076 ± 0.0294 | 39 | 0.4098 ± 0.0320 | 0.3199 |