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Table 4 NLR associated single CpG loci median (IQR) beta values in glioma patient subgroups

From: Immunomethylomic approach to explore the blood neutrophil lymphocyte ratio (NLR) in glioma survival

CpG loci

NLR status

Tumor grade

Mutation status

 

NLR high

NLR low

P

II/III

IV

P

IDH1

TERT

P

cg25938803

24.18 (22.72, 26.16)

33.55 (31.25, 39.00)

<0.001

28.33 (24.67, 32.50)

31.40 (26.20, 38.09)

0.1

30.73 (26.13, 34.66)

30.31 (24.44, 35.24)

0.8

cg00901982

20.63 (19.11, 22.61)

30.29 (26.67, 34.76)

<0.001

24.19 (21.17, 26.97)

27.71 (23.16, 34.32)

0.04

26.71 (23.00, 30.73)

24.69 (21.12, 32.06)

0.5

cg01591037

25.48 (23.58, 27.93)

33.87 (32.13, 39.76)

<0.001

30.14 (25.84, 33.75)

32.66 (27.94, 38.44)

0.1

32.01 (27.50, 36.35)

31.03 (25.84, 36.50)

0.6

cg10456459

26.49 (24.34, 28.20)

38.02 (35.68, 43.86)

<0.001

32.19 (27.47, 35.90)

36.44 (27.72, 44.06)

0.05

36.14 (28.20, 39.10)

32.97 (27.36, 39.06)

0.5

cg03621504

20.23 (18.28, 21.37)

26.25 (23.76, 30.42)

<0.001

22.47 (20.74, 26.12)

23.76 (21.39, 29.92)

0.2

23.66 (20.89, 26.40)

22.90 (20.88, 26.56)

0.8

  1. Note: Beta values are represented as percentages (beta values times 100). Median differences between groups were tested using a Mann-Whitney U test