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Table 1 Pathological and clinical characteristics of BC patient series

From: CDH22 hypermethylation is an independent prognostic biomarker in breast cancer

Variable

Frequency (%)

BC subtype

 LA

20/142 (14.1)

 LB

44/142 (31.0)

 LH

33/142 (23.2)

 H

21/142 (14.8)

 TN

24/142 (16.9)

Grade

 I

25/142 (17.6)

 II

59/142 (41.5)

 III

58/142 (40.8)

Lymph node involvement

 No

68/139 (48.9)

 Yes

71/139 (51.1)

Stage

 I

49/138 (35.5)

 IIA

34/138 (24.6)

 IIB

27/138 (19.6)

 IIIA

19/138 (13.7)

 IIIC

9/138 (6.5)

Age (years)

Mean 60

Range 30–95

Tumour size (cm)

Mean 2.2

Range 0.3–10.0

Progression-free survival (months)

Mean 82.9

Range 1–208

 No

115/141 (81.6)

 Yes

26/141 (18.4)

Overall survival (months)

Mean 86.9

Range 1–208

 Exitus

27/140 (19.3)

Chemotherapy

 No

49/138 (35.5)

 Yes

89/138 (64.5)

Hormone therapy

 No

43/136 (31.6)

 Yes

93/136 (68.4)

  1. BC subtypes: LA luminal A, LB luminal B/HER2-negative, LH luminal B/HER2-positive, H HER2, TN triple-negative