Table 1 Demographic and relevant clinical features of CF patients and controls
From: DNA methylation at modifier genes of lung disease severity is altered in cystic fibrosis
Discovery set (METHYLCF) | Replication set (FrGMC) | |||||||
|---|---|---|---|---|---|---|---|---|
C (n = 24) | CF (n = 48) | Mild (n = 23) | Intermediary (n = 13) | Severe (n = 12) | CF (n = 30) | Mild (n = 18) | Severe (n = 12) | |
Age, yeara | 37 | 26 | 34 | 25.5 | 22 | 24.5 | 27.0 | 23.5 |
Sex, M:F | 13:11 | 32:16 | 17:6 | 11:2 | 4:8 | 19:11 | 14:4 | 5:7 |
BMI (kg/m2)a | 20.9 | 22.1 | 20.5 | 19.8 | 19.9 | 21.4 | 18.0 | |
Weight (kg)a | 60.0 | 62.0 | 60.0 | 52.0 | 56.0 | 60.0 | 45.5 | |
Height (cm)a | 170 | 170 | 171 | 168 | 168.0 | 170.0 | 161.5 | |
FEV1%a | 48.0 | 64.8 | 48.0 | 41.5 | 91.0 | 102.0 | 24.0 | |
FVC %a | 74.0 | 87.0 | 67.0 | 66.5 | 98.5 | 105.0 | 46.0 | |
% PI | 100 | 100 | 100 | 100 | ||||
% Diabetes | 36.7 | 47.8 | 23.0 | 33.3 | ||||
% Atopy | 28.3 | 31.8 | 23.1 | 27.3 | ||||
% P. Aeruginosa | 93.9 | 91.3 | 100 | 90.9 | ||||
% MRSA | 34.1 | 22.7 | 30.8 | 60.0 | ||||
% Aspergillus | 18.2 | 26.1 | 14.3 | 20.0 | ||||