From: Integrating DNA methylation and microRNA biomarkers in sputum for lung cancer detection
miRNAs | AUC (95Â % CI) | Sensitivity (95Â % CI) | Specificity (95Â % CI) | P value |
---|---|---|---|---|
miR-31 | 0.76 (0.70 to 0.83) | 61.66 (55.35 to 67.68) | 81.86 (76.23 to 86.83) | <0.001 |
miR-21 | 0.80 (0.72 to 0.86) | 79.47 (72.38 to 82.94) | 70.98 (65.48 to 77.46) | <0.001 |
miR-210 | 0.84 (0.78 to 0.90) | 76.58 (68.35 to 80.13) | 81.16 (75–23.37 to 86.18) | <0.001 |
Combined use of 3 miRNAs | 0.89 (0.85 to 0.94) | 81.48 (68.5 to 90.75) | 85.91 (72.41 to 94.25) | <0.001 |