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Table 4 The expression of 3 miRNAs in sputum of a training set of stage I NSCLC patients and smokers with benign pulmonary nodules

From: Integrating DNA methylation and microRNA biomarkers in sputum for lung cancer detection

miRNAs

AUC (95 % CI)

Sensitivity (95 % CI)

Specificity (95 % CI)

P value

miR-31

0.76 (0.70 to 0.83)

61.66 (55.35 to 67.68)

81.86 (76.23 to 86.83)

<0.001

miR-21

0.80 (0.72 to 0.86)

79.47 (72.38 to 82.94)

70.98 (65.48 to 77.46)

<0.001

miR-210

0.84 (0.78 to 0.90)

76.58 (68.35 to 80.13)

81.16 (75–23.37 to 86.18)

<0.001

Combined use of 3 miRNAs

0.89 (0.85 to 0.94)

81.48 (68.5 to 90.75)

85.91 (72.41 to 94.25)

<0.001

  1. Abbreviations: AUC the area under receiver operating characteristic curve, CI confidence interval