From: Increased global placental DNA methylation levels are associated with gestational diabetes
Model A Constant −8.647 ± 1.589; p < 0.0001 | B | S.E. | Sig. | Exp(B) | 95 % CI for Exp(B) | |
Lower | Upper | |||||
 Maternal age, years | 0.061 | 0.026 | 0.017 | 1.063 | 1.011 | 1.118 |
 BMI beginning of pregnancy, kg/m2 | 0.067 | 0.025 | 0.008 | 1.069 | 1.018 | 1.124 |
 S/p 2 or more miscarriages, % | −0.128 | 0.502 | 0.798 | 0.880 | 0.329 | 2.351 |
 Ethnicity (Caucasian, other) | −0.111 | 0.558 | 0.842 | 0.895 | 0.300 | 2.669 |
 Diabetes in family (yes/no) | −0.318 | 0.289 | 0.271 | 0.728 | 0.413 | 1.281 |
 Placental DNA methylation, % | 0.879 | 0.267 | 0.001 | 2.408 | 1.427 | 4.063 |
Model B Constant −5.240 ± 1.275; p < 0.0001 | B | S.E. | Sig. | Exp(B) | 95 % CI for Exp(B) | |
Lower | Upper | |||||
 Maternal age, years | 0.061 | 0.026 | 0.017 | 1.063 | 1.011 | 1.118 |
 BMI beginning of pregnancy, kg/m2 | 0.073 | 0.025 | 0.004 | 1.076 | 1.024 | 1.13 |
 S/p 2 or more miscarriages, (%) | −0.143 | 0.501 | 0.775 | 0.867 | 0.325 | 2.314 |
 Ethnicity (Caucasian, other) | −0.139 | 0.554 | 0.802 | 0.87 | 0.294 | 2.579 |
 Diabetes in family (yes/no) | −0.314 | 0.289 | 0.277 | 0.731 | 0.415 | 1.286 |
 Placental DNA methylation (grouped) | 1.098 | 0.292 | 0.0002 | 2.999 | 1.691 | 5.316 |