Table 4 Immunohistochemical staining density of different study groups
Antibody | Control (I) | PDAC w CTX | PDAC w/o CTX | p | |
|---|---|---|---|---|---|
Good response (II) | Bad response (III) | ||||
PTEN | |||||
+4 | 3 | 1 | 0 | 0 | I vs. II: 0.0901 |
+3 | 6 | 7 | 6 | 0 | I vs. III: 0.0003 |
+2 | 4 | 14 | 16 | 12 | II vs. III: 0.0394 |
+1 | 0 | 3 | 17 | 15 | |
DCK | |||||
+4 | 7 | 10 | 6 | 1 | I vs. II: 0.7549 |
+3 | 4 | 8 | 13 | 16 | I vs. III: 0.0287 |
+2 | 2 | 6 | 15 | 9 | II vs. III: 0.1147 |
+1 | 0 | 1 | 5 | 1 | |
HuR | |||||
+4 | 0 | 0 | 0 | 0 | I vs. II: 0.0687 |
+3 | 5 | 2 | 3 | 1 | I vs. III: 0.0137 |
+2 | 5 | 13 | 13 | 8 | II vs. III: 0.3054 |
+1 | 3 | 10 | 23 | 18 | |
MDR-1 | |||||
+4 | 0 | 0 | 0 | 0 | I vs. II: 0.7427 |
+3 | 0 | 1 | 7 | 1 | I vs. III: 0.1068 |
+2 | 2 | 3 | 11 | 5 | II vs. III: 0.0426 |
+1 | 11 | 21 | 21 | 21 | |
MRP-1 | |||||
+4 | 9 | 1 | 4 | 1 | I vs. II: 0.00001 |
+3 | 4 | 3 | 12 | 3 | I vs. III: 0.0001 |
+2 | 0 | 6 | 11 | 10 | II vs. III: 0.1005 |
+1 | 0 | 15 | 12 | 13 | |
BCRP-1 | |||||
+4 | 2 | 0 | 0 | 0 | I vs. II: 0.00003 |
+3 | 8 | 1 | 7 | 2 | I vs. III: 0.0005 |
+2 | 3 | 12 | 24 | 19 | II vs. III: 0.0378 |
+1 | 0 | 12 | 8 | 6 | |
VEGF-1 | |||||
+4 | 10 | 0 | 1 | 0 | I vs. II: <0.0001 |
+3 | 3 | 4 | 6 | 2 | I vs. III: <0.0001 |
+2 | 0 | 14 | 23 | 12 | II vs. III: 0.8456 |
+1 | 0 | 7 | 9 | 13 | |