Fig. 4

PPAR-γ mRNA level and promoter methylation predict outcomes of ACHBLF patients. a The mRNA level of PPAR-γ in survivors (n = 37) was significantly higher than that in non-survivors (n = 44). b Kaplan-Meier graph showed that survival probability of unmethylated group (n = 30) was higher than methylated group (n = 51) in patients with ACHBLF. Serial PPAR-γ mRNA expression level in part of survivors (n = 11) (c) and non-survivors (n = 16) (d). e An overview of dynamic change of PPAR-γ mRNA expression level in part of survivors (n = 11) and non-survivors (n = 16). f The receiver operating characteristic (ROC) curves of PPAR-γ expression level, PPAR-γ promoter methylation, and MELD score for predicting 3-month mortality of patients with ACHBLF are shown (n = 81). The areas under the ROC curve (AUC) are noted. *P < 0.05, **P < 0.01