Figure 2From: DNA methylation of the allergy regulatory gene interferon gamma varies by age, sex, and tissue type in asthmaticsComparison of IFNγ promoter methylation levels by tissue type and CpG site stratified by age. Children <18 years, n = 27, adults ≥18 years, n = 47. Children had significantly higher CD4+ methylation levels at both CpG sites (-186 and -54: P <0.01). The methylation level of buccal cells was also significantly higher in children compared with adults at CpG -186 (P = 0.03) but not CpG -54 (P = 0.66).Back to article page