Figure 3From: LINE-1 hypomethylation is neither present in rectal aberrant crypt foci nor associated with field defect in sporadic colorectal neoplasiaEvaluation of long interspersed element-1 (LINE-1) methylation in normal colorectal mucosa as a potential field defect. (A) LINE-1 methylation levels in normal rectal mucosa (NRM) stratified by colon cancer (CC) risk group. (B) LINE-1 methylation levels in NRM compared with normal mucosa from the descending colon (NDM). Box-and-whisker plot indicating the median methylation level expressed as a percentage (horizontal line), 25th and 75th percentile (box), and maximum and minimum levels (whiskers).Back to article page