CpG site | Position relative to ATG | % of methylated clones within the 5′ CpG island flanking exon 1β | |||
---|---|---|---|---|---|
Tumor samples | Normal colon mucosa | Tumors with diffuse p53 overexpression pattern | Tumors with restricted p53 overexpression pattern | ||
1 | −69 | 13 | 5 | 3 | 17 |
2 | −43 | 17 | 1 | 0 | 24 |
3 | −40 | 22 | 1 | 0 | 31 |
4 | −35 | 25 | 4 | 0 | 36 |
5 | −28 | 22 | 2 | 0 | 31 |
6 | −22 | 19 | 2 | 0 | 27 |
7 | −10 | 22 | 5 | 3 | 30 |
8 | −7 | 21 | 3 | 0 | 30 |
9 | +4 | 30 | 5 | 3 | 41 |
10 | +25 | 41 | 8 | 37 | 43 |
11 | +31 | 42 | 12 | 43 | 41 |
12 | +34 | 45 | 12 | 50 | 43 |
13 | +36 | 43 | 18 | 43 | 43 |
14 | +38 | 34 | 12 | 33 | 34 |
15 | +42 | 43 | 13 | 43 | 43 |
16 | +47 | 41 | 15 | 53 | 36 |
17 | +50 | 45 | 9 | 50 | 43 |
18 | +52 | 43 | 12 | 57 | 37 |
19 | +66 | 47 | 9 | 50 | 46 |
20 | +80 | 44 | 9 | 50 | 41 |
21 | +82 | 40 | 13 | 37 | 41 |
22 | +90 | 38 | 13 | 27 | 43 |
23 | +105 | 38 | 13 | 47 | 34 |
24 | +114 | 41 | 19 | 50 | 37 |
25 | +118 | 34 | 17 | 37 | 33 |
26 | +121 | 31 | 24 | 37 | 29 |
27 | +133 | 27 | 9 | 13 | 33 |