Fig. 3
From: Refining risk prediction in pediatric acute lymphoblastic leukemia through DNA methylation profiling
Time-Dependent Area Under the Curve and Kaplan-Meier Plots for Relapse-Free Survival Analysis. a–b Time-dependent Area Under the Curve (AUC) representing the accuracy of the cox models in the prediction of relapse free survival (RFS) in the training (a) and test (b) sets. The red line represents a cox model based on standard of care risk grouping, the blue line represents the cox model based on the relapse risk predictor (RRP), and the purple line represents the cox model integrating both methods. c–d Kaplan-Meier plots depicting the RFS for the patients assigned to the two groups denoted by the relapse risk predictor: high-RRP (coral line) and low-RRP (blue line) in the training (c) and test (d) sets