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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Tissue of origin prediction for cancer of unknown primary using a targeted methylation sequencing panel

Fig. 1

A Workflow for feature selection and classifier development. B t-distributed stochastic neighbor embedding (t-SNE) using methylation profiles of the 200 CpGs across the training cohort (n = 2215). ACC Adrenocortical carcinoma, BLCA Bladder urothelial carcinoma, BRCA Breast invasive carcinoma, CESC Cervical squamous cell carcinoma and endocervical adenocarcinoma, COAD Colon adenocarcinoma, LAML Acute myeloid leukemia, LIHC Liver hepatocellular carcinoma, LUAD Lung adenocarcinoma, LUSC Lung squamous cell carcinoma, MESO Mesothelioma, PAAD Pancreatic adenocarcinoma, PCPG Pheochromocytoma and paraganglioma, PRAD Prostate adenocarcinoma, SARC Sarcoma, SKCM Skin cutaneous melanoma, STAD Stomach adenocarcinoma, TGCT Testicular germ cell tumors, THCA Thyroid carcinoma, UCEC Uterine corpus endometrial carcinoma, UVM Uveal melanoma

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Clinical Epigenetics

ISSN: 1868-7083

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