Self-control is associated with health-relevant disparities in buccal DNA-methylation measures of biological aging in older adults

Table 1 Indirect path estimates of DNA-methylation measures of biological aging statistically accounting for associations of self-control with health

	Accelerated biological age						Pace of aging
	PhenoAge acceleration			GrimAge acceleration			DunedinPACE
	B	95% CI	p	B	95% CI	p	B	95% CI	p
Self-control → disease severity
Total effect	− .22	[− .28, − .16]	< .001	− .22	[− .28, − .16]	< .001	− .22	[− .28, − .16]	< .001
Direct effect	− .21	[− .27, − .15]	< .001	− .20	[− .27, − .14]	< .001	− .22	[− .28, − .15]	< .001
Indirect effects	− .01	[− .03, .02]	.09	− .02	[− .04, − .00]	.03	− .01	[− .02, 01]	.47
Self-control → health
Total effect	.22	[.15, .29]	< .001	.22	[.15, .29]	< .001	.22	[.15, .29]	< .001
Direct effect	.21	[.14, .28]	< .001	.21	[.14, .27]	< .001	.22	[.15, .29]	< .001
Indirect effects	.01	[− .00, .03]	.10	.02	[.00, .03]	.04	− .00	[− .01, .01]	.85

ISSN: 1868-7083