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Fig. 2 | Clinical Epigenetics

Fig. 2

From: YAP represses intestinal inflammation through epigenetic silencing of JMJD3

Fig. 2

Loss of YAP in IECs aggravates DSS-induced colitis in mice. A Immunohistochemical analyses of YAP expressions are shown. B–E YAPf/f and YAPIEC−/− mice were fed with 2.5% DSS in drinking water, and loss of body weights (B), DAI (C) and colon length (D, E) were recorded. F H&E-stained sections of colon tissues collected on day 9 from 2.5% DSS-treated YAPf/f and YAPIEC−/− mice. G, H Relative protein expression levels of intestinal barrier protein in the whole colon of YAPf/f and YAPIEC−/− mice. I Relative mRNA expression levels of chemokines in the whole colon of YAPf/f and YAPIEC−/− mice

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