Fig. 1

YAP increased in UC patients and DSS-induced colitis model. A Boxplot of YAP expression in healthy controls and UC patients (using dataset GSE75214; n = 108). B qPCR analysis of YAP in healthy controls (n = 16) and UC patients (n = 17), respectively. C–D Relative protein levels of YAP in healthy controls and UC patients, respectively. E–H C57BL/6 mice were fed with 2.5% DSS in drinking water, and loss of body weights (E), DAI (F) and colon length (G, H) were recorded. I H&E-stained sections of colon tissues collected on days 0, 5 and 9 from 2.5% DSS-treated C57BL/6 mice. J qPCR analysis of YAP in NC (n = 7) and 2.5% DSS-induced colitis mice (n = 7). K Relative protein levels of YAP in NC and 2.5% DSS-induced acute colitis mice. L Immunohistochemical analyses of YAP expressions are shown