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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Long non-coding RNA ACTA2-AS1 suppresses metastasis of papillary thyroid cancer via regulation of miR-4428/KLF9 axis

Fig. 1

ACTA2-AS1 levels were downregulated in papillary thyroid carcinoma (PTC). A qRT-PCR analysis of the levels of ACTA2-AS1 in normal thyroid tissues (n = 19), PTC tissues without metastasis (n = 19), and PTC tissues with lymph node metastasis (n = 11). The data were log2-transformed (2–ΔΔCt). B qRT-PCR analysis of the levels of ACTA2-AS1 in stage I/II (n = 18) and stage III/IV (n = 12) PTC tissues. The data were log2-transformed (2–ΔΔCt). C The levels of ACTA2-AS1 were analyzed in 512 thyroid carcinoma tissues and 337 normal tissues in The Cancer Genome Atlas (TCGA)/Genotype-Tissue Expression (GTEx) datasets from GEPIA. D qRT-PCR analysis of ACTA2-AS1 levels in BCPAP, TPC1, and Nthy-ori 3–1 cells. *p < 0.05, **p < 0.01

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