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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Malignant peripheral nerve sheath tumor (MPNST) and MPNST-like entities are defined by a specific DNA methylation profile in pediatric and juvenile population

Fig. 3

CNV and survival analysis results. A-D: Cumulative CNV plots representing the proportion of copy number gains (red) or losses (blue) across all chromosomes in MPNST samples of group 1 A, ANF samples B, high-grade C and low-grade D sarcomas with MPNST-like DNAm profile. E: Kaplan–Meier survival curve for the different histological types included in the study (MPNST in yellow, atypical neurofibroma in blue, MPNST-like DNAm profile – High grade in red, MPNST-like DNAm profile – Low grade in green. F: Kaplan–Meier curve representing the effect of CDK2A/B loss (absent in blue, present in red) on the survival of patients with MPNST histology and MPNST DNAm profile

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Clinical Epigenetics

ISSN: 1868-7083

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