Fig. 2

DNA methylation analysis results. A: PCA clustering of sarcoma DNAm profiling. Histological diagnosis is represented by point color, DNAm profiling results according to the Sarcoma Classifier are represented by point shape; clusters are indicated by green or red margins. B: Barplot of top 5 GSEA results for the differentially methylated genes between cluster 1 and cluster 2. For each enriched geneset (Y axis), bar length (X axis) represents the number of differentially methylated genes included in the geneset, and bar color represents the adjusted p-value. C: PCA clustering results where H3K27me3 status is represented by sample color