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Fig. 3 | Clinical Epigenetics

Fig. 3

From: TET2-mediated ECM1 hypomethylation promotes the neovascularization in active proliferative diabetic retinopathy

Fig. 3

Validation of TET2-targeted hypomethylated upregulated genes. A Expression of TET2 and the three key genes. B Protein levels of three key genes in NC and HG groups. C Quantitative analysis of promoter methylation levels of the three key genes. D Agarose gel electrophoresis results of MS-PCR products of the key genes. MS-PCR, methylation-specific PCR; M, methylation bands; U, unmethylated bands; M/U, quantifying the ratio of the intensity of the methylated band to the unmethylated band; NC, normal control; HG, high glucose

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