Fig. 6
From: Histone acetylation: a key determinant of acquired cisplatin resistance in cancer
Effect of 2DG treatment on tumorigenic potential of cisplatin resistant cells. A Estimation of tumor progression of CisR/HeLa cells after Cisplatin or 2DG treatment. ↑ represents 1 round of dose. B Representative image for tumor size after 8 weeks of treatment in different groups. C Effect of 2DG on histone PTMs and Caspase3 in cisplatin resistant xenograft tissues. Bar graph representing the H-Score desired antigens in the experimental setup. The scale bar denotes 10 μm. The bar graph represents H-Score for mean ± S.E.M. from 4–5 biological replicates. *p < 0.05, and ****p < 0.0001