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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Histone acetylation: a key determinant of acquired cisplatin resistance in cancer

Fig. 5

Role of histone acetylation in survival of cisplatin resistant cells. A Western blot analysis to check the effect of cisplatin in time-dependent manner on histone PTM levels. T.P. depicts Time point. B Percent apoptotic cells determined using Annexin-FITC/PI staining in CisR/HeLa cells. C Long-term survival assay upon 2DG treatment in CisR/HepG2 cells. Data with error bar represent mean ± S.D from 3 biological replicates *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001

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