Methylation of serotonin regulating genes in cord blood cells: association with maternal metabolic parameters and correlation with methylation in peripheral blood cells during childhood and adolescence

Table 3 Hierarchical linear regression analysis of maternal metabolic parameters as predictors of MAOA methylation (mean of CpG sites #1 to #9) in cord blood cells

Step	Variable	B	SE (B)	p (B)	R²	p (R²)	ΔR²	p (ΔR²)
1	Neonatal sex	− 29.51	1.55	< 0.0001	0.644	< 0.0001
2	Neonatal sex	− 29.78	1.55	< 0.0001	0.649	< 0.0001	0.004	0.124
2	pBMI	0.20	0.13	0.124	0.649	< 0.0001	0.004	0.124
3	Neonatal sex	− 29.71	1.56	< 0.0001	0.649	< 0.0001	0.001	0.557
	pBMI	0.17	0.13	0.189
	GWG	− 0.08	0.14	0.557
4	Neonatal sex	− 29.71	1.56	< 0.0001	0.651	< 0.0001	0.001	0.365
	pBMI	0.15	0.14	0.280
	GWG	− 0.06	0.14	0.683
	GTS	1.48	1.64	0.365
5	Neonatal sex	− 30.05	1.63	< 0.0001	0.653	< 0.0001	0.002	0.777
	pBMI	0.11	0.14	0.440
	GWG	− 0.06	0.15	0.675
	GTS	1.54	1.67	0.358
	Parity	1.48	1.66	0.375
	Maternal age	− 0.02	0.17	0.906
	Birth weight	0.00	0.00	0.591

ISSN: 1868-7083