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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Tumor microenvironment deconvolution identifies cell-type-independent aberrant DNA methylation and gene expression in prostate cancer

Fig. 6

TME correction in DEA identifies 51 tumor-specific genes when comparing tumor versus non-tumor groups. The differential expression analysis pathological stage and for age, sex, Gleason score, preoperative PSA levels, pathological stage, and immune and angiogenic cell-type proportions from the second HiTIMED hierarchical level. Genes with significant adjusted p-values (FDR Q-value < 0.05) are shown in blue, those with log2 fold change (log2(tumor expression/control expression)) whose absolute value is greater than one in green, and genes that are both are shown in red

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Clinical Epigenetics

ISSN: 1868-7083

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