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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Histone demethylase KDM4B accelerates the progression of glioblastoma via the epigenetic regulation of MYC stability

Fig. 2

KDM4B is essential for supporting cell survival, proliferation, migration, and invasion. A Morphology of cells was observed after knocking down KDM4B. B MTT curves of GBM cells after KDM4B knockdown. C Cells positive for BrdU staining after KDM4B knockdown are shown. D Analysis of colony formation in GBM cells after KDM4B knockdown. E The migration ability of KDM4B-knockdown GBM cells was measured by the wound healing test. F-G The migration and invasion ability of KDM4B-knockdown GBM cells were detected by transwell assays. **p < 0.01; ***p < 0.001; ns, not significant

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