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Fig. 3 | Clinical Epigenetics

Fig. 3

From: EZH2 K63-polyubiquitination affecting migration in extranodal natural killer/T-cell lymphoma

Fig. 3

TRIP12 modulates EZH2 target gene expression. A, B Relative mRNA expression of canonically-repressed and noncanonically-activated target genes of EZH2 upon siRNA-mediated knockdown of TRIP12 in YT (A) and NKYS (B). C, D Relative mRNA expression of canonically-repressed and noncanonically-activated target genes of EZH2 upon TRIP12 or empty vector transfection in YT (C) and NKYS (D). Results are mean ± SD. N = 3; N.S. not significant; *p < 0.05; **p < 0.01; ***p < 0.001

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